Artificial Lymph Nodes????

Lymphatic vessel

Lymphatic vessel (Photo credit: Wikipedia)

I wonder if in the future Artificial Lymph nodes could be created….. Imagine the possibilities that could open up for the treatment of all types of Lymphoedema…it is good to see that research is being done in this area….

The Sunnybrook Research Institute

“The lymphatic research group is part of the biological sciences platform and the Brain Sciences Research Program at Sunnybrook Research Institute (SRI). Our principal investigator, Dr. Miles Johnston, has studied the lymphatic circulatory system for over 30 years.

We are investigating several issues related to the relationship between lymphatic vessels and disease, including:

The role of lymphatic injury in the generation of post-surgical lymphedema in breast cancer.

We are fully affiliated with the University of Toronto.

The loss of the lymph nodes in cancer patients may have a much more negative impact on tissue fluid balance than has been considered in the past. Available evidence suggests that the absorption of protein-free water into the capillaries of the nodes has an important role in the regulation of pressure and volume in downstream anatomical elements of the lymphatic system. The autologous transplantation of lymph nodes into the surgical resection site could facilitate the restoration of normal lymph transport in the affected limb. However, the removal of a normal lymph node could lead to donor site morbidity.

We are investigating the possibility of developing an artificial lymph node that could be implanted into the surgical resection site. We are attempting to create an implant that will stimulate new blood vessel and lymphatic vessel growth resulting in the recreation of an intact lymphatic network.

Current therapeutic measures are applied to patients with entrenched edema and the outcome is often unsatisfactory. In the case of breast cancer-related post-surgical lymphedema, the timeline of the disorder can be linked to the removal of lymph nodes. Therefore, it is likely that a higher success rate may be achieved with treatment started early (lymph node transplantation or its artificial equivalent) since the chronic sequel of events leading to lymphedema might be prevented”.... Ref.. Sunnybrook Research Institute website


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12 thoughts on “Artificial Lymph Nodes????

  1. Wouldn’t that be amazing – only one incision and area to heal post surgery and imagine if they could be implanted at the time of the original surgery. I hope they are successful … and soon!

  2. Well now they tell us about artificial lymph nodes. Gee would have saved me from the big incision under my arm!
    So happy to see so much research being done on the damage lymph node removal does. So many people suffering from the aftermath of having them removed. It’s about time the world woke up and tried to come up with a solution other than here’s your compression hose and your pump. Have a nice life!

    • Well said Bridget..,I was thrilled to see that there was money being spent on such research.. At least someone is taking note.. This would also be a huge benefit to those with primary Lymphoedema..

  3. Yes Thank you Helen to mention it… also for primary lymphedema it would mean a big thing. As for now, also with the lymph node transfer, primary lymphedema is much more risky and doctors are not so much pro lymph node transfer… So not much hope for us… But artificial lymph nodes , or development of drugs (based on genetic testing) would be a huuuuge step forwards. Also I guess for other immune diseases, they would be great…
    But it seems like science fiction to me: lymph nodes are sooo tiny!
    @ Bridget Benjamin: did you have a lymph node transfer?

  4. Pingback: The search for the Holy Grail- a cure for Lymphodema? (Pre-operative thoughts) | lymphodemalifeinkorea

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